| Week 11 | Alberto | Eric | Greg | JoAnn | Joe | Karl | Kathy | Neal/Joc | Olga | Sandy | ||||
| Thursday, November 19 | ||||||||||||||
| Away | Home | Stadium | Time | Network | ||||||||||
| Miami (4-5, Road: 1-3) | Carolina (4-5, Home: 2-2) | Bank of America Stadium | 8:20 PM | NFLN | Carolina | Miami | Carolina | Carolina | Carolina | Carolina | Carolina | Miami | Carolina | Carolina |
| Sunday, November 22 | ||||||||||||||
| Pittsburgh (6-3, Road: 2-2) | Kansas City (2-7, Home: 0-4) | Arrowhead Stadium | 1:00 PM | CBS | Pittsburgh | Pittsburgh | Pittsburgh | Pittsburgh | Pittsburgh | Pittsburgh | Pittsburgh | Pittsburgh | Pittsburgh | Pittsburgh |
| Inianapolis (9-0, Road: 4-0) | Baltimore (4-4, Home: 3-1) | M&T Bank Stadium | 1:00 PM | CBS | Indianapolis | Indianapolis | Indianapolis | Indianapolis | Indianapolis | Indianapolis | Indianapolis | Indianapolis | Indianapolis | Indianapolis |
| Atlanta (5-4, Road: 1-4) | New York Giants (5-4, Home: 2-2) | Giants Stadium | 1:00 PM | FOX | New York Giants | Atlanta | New York Giants | New York Giants | New York Giants | Atlanta | New York Giants | New York Giants | New York Giants | New York Giants |
| New Orleans (9-0, Road: 4-0) | Tampa Bay (1-8, Home: 1-4) | Raymond James Stadium | 1:00 PM | FOX | New Orleans | New Orleans | New Orleans | New Orleans | New Orleans | New Orleans | New Orleans | New Orleans | New Orleans | New Orleans |
| Buffalo (3-6, Road: 2-3) | Jacksonville (5-4, Home: 3-1 | Jacksonville Municipal Stadium | 1:00 PM | CBS | Buffalo | Jacksonville | Jacksonville | Jacksonville | Jacksonville | Jacksonville | Jacksonville | Jacksonville | Jacksonville | Buffalo |
| Cleveland (1-7, Road: 1-4) | Detroit (1-8, Home: 1-3) | Ford Field | 1:00 PM | CBS | Cleveland | Detroit | Detroit | Detroit | Detroit | Detroit | Detroit | Cleveland | Detroit | Cleveland |
| Washington (3-6, Road: 0-4) | Dallas (6-3, Home: 3-1) | Cowboys Stadium | 1:00 PM | FOX | Dallas | Dallas | Dallas | Washington | Dallas | Dallas | Dallas | Dallas | Dallas | Dallas |
| Seattle (3-6, Road: 0-4) | Minnesota (8-1, Home: 4-0) | Mall of America Field | 1:00 PM | FOX | Minnesota | Minnesota | Minnesota | Minnesota | Minnesota | Minnesota | Minnesota | Minnesota | Minnesota | Minnesota |
| San Francisco (4-5, Road: 1-3) | Green Bay (5-4, Home: 3-2) | Lambeau Field | 1:00 PM | FOX | Green Bay | Green Bay | Green Bay | Green Bay | Green Bay | Green Bay | Green Bay | Green Bay | Green Bay | Green Bay |
| Arizona (6-3, Road: 4-0) | St. Louis (1-8, Home: 0-4) | Edward Jones Dome | 4:05 PM | FOX | Arizona | Arizona | Arizona | Arizona | Arizona | Arizona | Arizona | Arizona | Arizona | Arizona |
| New York Jets (4-5, Road: 2-2) | New England (6-3, Home: 5-0) | Gillette Stadium | 4:15 PM | CBS | New England | New England | New England | New England | New England | New York Jets | New England | New England | New England | New England |
| Cincinnati (7-2, Road: 4-0) | Oakland (2-7, Home: 1-4) | Oakland Coliseum | 4:15 PM | CBS | Cincinnati | Cincinnati | Cincinnati | Cincinnati | Cincinnati | Cincinnati | Cincinnati | Cincinnati | Cincinnati | Cincinnati |
| San Diego (6-3, Road: 3-1) | Denver (6-3, Home: 3-1) | Invesco Field at Mile High | 4:15 PM | CBS | San Diego | San Diego | San Diego | Denver | San Diego | San Diego | San Diego | San Diego | Denver | San Diego |
| Philadelphia (5-4, Road: 2-2) | Chicago (4-5, Home: 3-1) | Soldier Field | 8:20 PM | NBC | Philadelphia | Philadelphia | Philadelphia | Philadelphia | Philadelphia | Chicago | Philadelphia | Philadelphia | Philadelphia | Philadelphia |
| Sunday, November 23 | ||||||||||||||
| Away | Home | Stadium | Time | Network | ||||||||||
| Tennessee (3-6, Road: 1-4) | Houston (5-4, Home: 2-2) | Reliant Stadium | 8:30 PM | ESPN | Houston | Tennessee | Houston | Houston | Houston | Tennessee | Houston | Houston | Houston | Tennessee |
| Alberto | Eric | Greg | JoAnn | Joe | Karl | Kathy | Neal | Olga | Sandy | |||||
| 10 | 13 | 12 | 10 | 12 | 10 | 12 | 12 | 11 | 11 |